If it does, move it back and try another folder. Move one of iTunes preference folders to the desktop and see if iTunes not responding on Windows 10 error persists.

To repair QuickTime, go to Control Panel, then Programs and Features, click QuickTime, and tap on Repair. If there's no APSDaemon.exe file, remove SC files, and then restart computer and iTunes to have a try. From the iTunes Media Folder Location windows, navigate to the new drive (Backup Plus for example). In the iTunes app on your PC, choose Edit > Preferences, then click. If this solution works, take the following actions to avoid doing the same thing every time your restart your Windows 10 computer: go to Run > enter msconfig > click Startup tab > uncheck 'Apple Push' > hit on OK > reboot computer. Also in the Advanced Preferences windows, click Change. Use iTunes preferences to change options for your iTunes library, how music plays, and more. Then go back to iTunes and see if the issue gets fixed.

Navigate to Processes tab, locate APSDaemon.exe and close it. Close iTunes, and then open Task Manager.

Itunes preferences windows 10